Abstract
Hypothermia therapy in neonatal hypoxic-ischemic encephalopathy: Current perspectives, combination therapy and future directions
Moaaz Abo Zeed 1*, Maher Mohamad Najm 2,3, Arwa Ajaj 4, Mohamad Ahmad Ajaj 5
Keywords: Therapeutic hypothermia, Hypoxicischemic encephalopathy, Cooling, Neonatal neuroprotection
DOI: 10.18231/j.yjom.2024.019
DOI URL: https://doi.org/10.18231/j.yjom.2024.019
Publish Date: 15-12-2024
Pages: 182 - 189
Views: 31
Downloads: 45
Author Affiliation:
1Neonatal Intensive Care Unit, Women's Wellness and Research Center, Hamad Medical Corporation, Doha, Qatar
2,3 Pediatric Emergency Center, Hamad Medical Corporation, Doha, Qatar,
4Sidra Medicine, Ar-Rayyan, Qatar
5Shmaisani Hospital, University of Jorden, Jordan
Abstract
Hypoxic-ischemic encephalopathy (HIE) in neonates, resulting from oxygen deprivation during birth, is a significant cause of death and long-term disabilities. Therapeutic hypothermia has emerged as a pivotal intervention for improving neurological outcomes in infants with HIE. This review aims to summarize current practices, outcomes, and challenges of hypothermia therapy in neonatal HIE, and adjuvant therapies, along with future directions in this evolving field.