A rare case of bilateral lung metastasis from renal cell carcinoma 26 years after nephrectomy

Waleed Khaled Kaleem¹, Samira Awad Ba Nser², Rasheed Mohammed Bamekhlah³, Wadeea Saaeed Bin Gouth⁴, Mohammed Ahmad Bakrmom⁵

Keywords: Lung metastasis, Renal cell carcinoma, Side effects, Sunitinib

DOI: 10.32677/yjm.v2i2.4035

DOI URL: https://doi.org/10.32677/yjm.v2i2.4035

Publish Date: 28-09-2023

Pages: 108 - 111

Views: 2

Downloads: 4

Author Affiliation:

¹Assitant Profosser of Internal Medicine and Oncology, Oncology Consultant, 
²Medical Specialist, Department of Medicine, Ibn-Seena Teaching Hospital, Mukalla, Hadramout, Yemen
³Profosser of Internal Medicine, Senior Medical Consultant, Department of Medicine, 
⁴Profosser, Department of Radiology, 
⁵Medical Student Last Year, Department of Medicine, College of Medicine and Health Sciences, Hadramout University, 

Abstract

Renal cell carcinoma (RCC) is a malignant tumor that often metastasizes early. About 33% of RCC patients present with metastatic masses, mostly in the lungs. Our patient was a 66-year-old woman who had a left-sided nephrectomy for RCC 26 years ago. Prior to the current presentation, she sought medical advice for about a year because of her easy fatigability, which was attributed to her normocytic normochromic anemia. Incidentally, a mass was discovered in each lung, which was found histopathologically and immunohistochemically to be a metastasis of RCC. The patient received sunitinib, which is the standard treatment for patients with advanced RCC and metastases without benefit at initial doses and cycles. Consequently, the dose was increased up to four times the initial dose, and by the third cycle, side effects appeared in the form of impaired consciousness up to deep coma, hypertension, hypercarotenemia, pancytopenia, hyponatremia, hypokalemia, and subclinical hypothyroidism. She was taken to the hospital and then sadly passed away.