Abstract
Is glucose-6-phosphate dehydrogenase deficiency a risk factor for melioidosis?
Almurtada Razok1 , Zohaib Yousaf2 , Abdo Lutf3 , Musaed Alsamawi4
1Resident,
2Consultant, Department of Medicine, Hamad General Hospital, Doha, Qatar,
3Consultant, Rheumatology Division, 4Consultant, Infectious Diseases Division, Department of Medicine, Alkhor hospital, Qatar
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Abstract
Melioidosis is an infection that causes high morbidity and mortality. Predisposing risk factors include diabetes mellitus (DM) and immunocompromised state. We report a case of septic shock secondary to bacteremia caused by Burkholderia pseudomallei in a patient who is supposed to be previously healthy and subsequently diagnosed with DM and glucose-6-phosphate dehydrogenase (G6PD) deficiency. He completed 17 days of intravenous antibiotics followed by a 12-week course of oral trimethoprim/sulfamethoxazole. We postulate that G6PD deficiency could be a risk factor for melioidosis.