yemenjmedYemen Journal of MedicinecoVolume 1 Issue 1MultidisciplinaryEnglishJanuary - June 2022NNY20250325ArticleManagement of hypertriglyceridemia-induced pancreatitis – A review of updates from the past decadeEnglishY25Fateen Ata1EnglishNAdeel Ahmad Khan2EnglishYZohaib Yousaf1EnglishYAmmarChapra3EnglishY10.32677/yjm.v1i1.3347Hypertriglyceridemia-induced acute-pancreatitis (HTG-AP) is an important etiology of acute pancreatitis (AP). The treatment includes general management of AP with bowel rest, analgesia, and venous thromboembolism prophylaxis. Specific treatment of HTG-AP focuses on reducing serum triglyceride (TG) levels. Various modalities have been used, including heparin infusion, insulin infusion, plasmapheresis, and double filtration plasmapheresis (DFPP). However, the extent to which TG reduction translates into a clinical response remains unclear. This review highlights the emerging evidence on the management of HTG-AP. Insulin therapy and plasmapheresis remain treatment options to reduce TG. DFPP is an emerging treatment modality to reduce TG levels in patients with AP. However, to what extent this translates into a better clinical response is yet to be answered in large and prospective study designs.EnglishHypertriglyceridemia, Pancreatitis, Triglycerides, Hypertriglyceridemia-induced acute pancreatitishttps://www.yemenjmed.com/admin/abstract?id=3References16191. Lankisch PG, Apte M, Banks PA. Acute pancreatitis. Lancet 2015;386:85-96.2. Olson E, Perelman A, Birk JW. Acute management of pancreatitis: The key to best outcomes. Postgrad Med J 2019;95:328-33.3. Iannuzzi JP, King JA, Leong JH, et al. Global incidence of acute pancreatitis is increasing over time: A systematic review and meta-analysis. Gastroenterology 2022;162:122-34.4. Ouyang G, Pan G, Liu Q, et al. 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