yemenjmedYemen Journal of MedicinecoVolume 4 Issue 2MultidisciplinaryEnglishMay-August 2025NNY20250922ArticleLaparoscopic Cholecystectomy in Situs Inversus Totalis, Challenges From the Surgeon’s Perspective: A Case ReportEnglishY463467PrapancaNugraha1EnglishNAndriantoAndrianto2EnglishYRenoRudiman3EnglishY10.63475/yjm.v4i1.0158Situs inversus totalis (SIT) is a rare birth defect marked by a complete reversal of the positions of abdominal and thoracic organs, resembling a mirrored image. This condition can raise challenges both in diagnosis and treatment procedures. Management of cholelithiasis in SIT patients presents difficulties due to the anatomical differences. We present a case involving a 47-year-old male patient who experienced intermittent left upper abdominal pain over the course of 4 months; the pain had worsened in the last 2 months. The pain was felt radiating to the waist and left back and was accompanied by nausea and vomiting. After clinical assessment and radiological investigations, such as thoracic X-ray and abdominal ultrasound, the patient was suspected of having cholelithiasis and SIT. The patient underwent an elective laparoscopic cholecystectomy without complications and experienced an uneventful recovery. Several intraoperative adjustments were implemented to address the technical challenges arising from the underlying anatomical variation.EnglishSitus inversus totalis, cholelithiasis, cholecystitis, laparoscopic cholecystectomy, case reporthttps://www.yemenjmed.com/admin/abstract?id=238References1619