yemenjmedYemen Journal of MedicinecoVolume 1 Issue 1MultidisciplinaryEnglishJanuary - June 2022NNY20250327ArticlePrevalence of tuberculosis in Shabwah Governorate, Yemen: A cross-sectional studyEnglishY3637Hesham SaeedHezamEnglishNSaleh HusseinHumaidahEnglishY10.32677/yjm.v1i1.3447Background: There is a lack of data on current tuberculosis (TB) burden in Shabwah Governorates in Yemen. This study aimed to investigate the prevalence, epidemiology, and outcomes of TB disease in Shabwah Governorate, Yemen. Materials and Methods: This cross-sectional study was conducted at the National TB Program (NTP) Center in Ataq City, Shabwah Governorate, Yemen. The study involved TB patients of different ages who were notified at the center between January 1, 2021, and December 31, 2021. Results: We involved a total of 123 new active TB cases, including 86 (69.9%) with pulmonary TB (PTB) and 37 (30.1%) with extrapulmonary TB (EPTB). The total prevalence of TB disease during the year 2021 was 14.5 new TB cases per 100,000 population, while the median age of the study population was 34 years. The majority of the cases (23.6%) belonged to age group 15–24 years. There was a slightly higher preponderance of males 54.5% (n=67). EPTB was detected in 37 (30.1%) patients with lymph nodeTB being the most common manifestation [17 (46.0%)]. All patients received four-drug anti-TB therapies for 6–12 months. Most patients 111 (90.3%) were cured, and 2 (1.6%) patients died during the course of the disease, while 10 (8.1%) patients were lost during follow-up. Conclusion: The prevalence of TB in Shabwah Governorate was 14.5/100,000 population. Male patients and younger age groups were more affected, while the lymph nodes were the main extrapulmonary sites involved and the cure rate was 90.2%. The results of the study indicate the need to revise the notification form for active TB cases and to expand NTP activities to focus on targeted screening for active TB cases in high-risk groups to close the gap in unidentified TB cases.EnglishAcid-fast bacilli, Extrapulmonary tuberculosis, Prevalence, Pulmonary tuberculosishttps://www.yemenjmed.com/admin/abstract?id=16References16191. Global Tuberculosis Report 2021: Available from: https://www.who.int/ publications/i/item/9789240037021 [Last accessed on 2022 Apr 01].2. Deribew A, Deribe K, Dejene T, et al. Tuberculosis burden in Ethiopia from 1990 to 2016: Evidence from the global burden of diseases 2016 Study. Ethiop J Health Sci 2018;28:519-28.3. The World Bank. Available from: https://www.data.worldbank.org/indicator/ SH.TBS.INCD?locations=YE [Last accessed on 2022 Apr 01].4. Al Kalali FS, Mahyoub E, Al-Hammadi A, et al. Evaluation of the national tuberculosis surveillance system in sanaand;rsquo;a, Yemen, 2018: Observational study. JMIR Public Health Surveill 2021;7:27626.5. Puttoo AN, Shah NN, Tripathi S, et al. Prevalence of tuberculosis in the North Indian subcontinent Kashmir valley: A cross-sectional hospital-based study. J Clin Diagn Res 2022;16:10-4.6. Abdallah TM, Ali AA. Epidemiology of tuberculosis in Eastern Sudan. Asian Pac J Trop Biomed 2012;2:999-1001.7. Elsafi SS, Nour BM, Abakar AD, et al. Pulmonary tuberculosis among Sudanese individuals of White Nile state: Prevalence and role of the sociodemographic features and laboratory findings in the assessment of infection. J Microbiol Exp 2020;8:52-63.8. Garcand;iacute;a-Rodrand;iacute;guez JF, and;Aacute;lvarez-Dand;iacute;az H, Lorenzo-Garcand;iacute;a MV, et al. Extrapulmonary tuberculosis: Epidemiology and risk factors. Enferm Infecc Microbiol Clin 2011;29:502-9.9. Pang Y, An J, Shu W, et al. Epidemiology of extrapulmonary tuberculosis among inpatients, China, 2008-2017. Emerg Infect Dis. 2019;25:457-64.10. Tahseen S, Khanzada FM, Baloch AQ, et al. Extrapulmonary tuberculosis in Pakistan-a nation-wide multicenter retrospective study. PLoS One 2020;15:0232134.11. Jehangir F, Hashmi R, Lateef TK, et al. Prevalence and outcomes of tuberculosis treatment in a primary care center in Karachi, Pakistan. Arch Med 2020;12:1-6.12. Fatima R, Ejaz Q, Enarson DA, et al. Comprehensiveness of primary services in the care of infectious tuberculosis patients in Rawalpindi, Pakistan. Public Health Action 2011;1:13-5.13. Abdallah TM, Toum FE, Bashir OH, et al. Epidemiology of extra pulmonary tuberculosis in Eastern Sudan. Asian Pac J Trop Biomed 2015;5:505-8.14. Gomes T, Reis-Santos B, Bertolde A, et al. Epidemiology of extrapulmonary tuberculosis in Brazil: A hierarchical model. BMC Infect Dis 2014;14:9.15. Selmane S, Land;rsquo;Hadj M. Epidemiology and clinical characteristics of tuberculosis in leon bernard tuberculosis unit in Algeria. Int J Mycobacteriol 2020;9:254-60.16. Prakasha SR, Suresh G, Dand;rsquo;sa IP, et al. Mapping the pattern and trends of extrapulmonary tuberculosis. J Glob Infect Dis 2013;5:54-9.17. Kulchavenya E. Extrapulmonary tuberculosis: Are statistical reports accurate? Ther Adv Infect Dis 2014;2:61-70.18. Sreeramareddy CT, Panduru KV, Verma SC, et al. Comparison of pulmonary and extrapulmonary tuberculosis in Nepal-a hospital-based retrospective study. BMC Infect Dis 2008;8:8.19. Musellim B, Erturan S, Duman ES, et al. Comparison of extra-pulmonary and pulmonary tuberculosis cases: Factors influencing the site of reactivation. Int J Tuberc Lung Dis 2005;9:1220-3.20. Razanamparany VR, Mand;eacute;nard D, Aurand;eacute;gan G, et al. Extrapulmonary and pulmonary tuberculosis in antananarivo (Madagascar): High clustering rate in female patients. J Clin Microbiol 2002;40:3964-9.21. Ohene SA, Bakker MI, Ojo J, et al. Extra-pulmonary tuberculosis: A retrospective study of patients in Accra, Ghana. PLoS One 2019;14:0209650.22. Yang Z, Kong Y, Wilson F, et al. Identification of risk factors for extra pulmonary tuberculosis. Clin Infect Dis 2004;38:199-205.